Agenda IBD Cutting Edge 2025: Where Innovation, Trials, and Multidisciplinary Care Intersect

9:30 a.m.                           

Registration, Refreshments & View Exhibits

10:30 a.m.         

Welcome & Educational Overview

Amy Lightner, MD – Scripps Clinic San Diego

HOW TRANSLATIONAL SCIENCE IS RELEVANT TO THE CLINIC

Moderators: Marla Dubinksy, MD and Howard Hang, PhD

10:40 a.m.         

Developing New Drug Targets: Considerations and Pre-clinical Logistics

Arnab Chatterjee, PhD – Scripps Research San Diego

10:55 a.m.         

Regenerative Medicine Beyond Cell Therapy: How We Might Break the Therapeutic Ceiling

Michael Bollong, PhD – Scripps Research San Diego

11:10 a.m.         

Biological Drivers of Response to Therapies

Maria Abreu, MD – Cedars-Sinai Medical Center

11:25 a.m.

Targeting Regulatory T-Cells in IBD

Scott Snapper, MD, PhD – Boston Children’s Hospital

11:40 a.m.        

The Role of Artificial Intelligence in Drug Discovery

Pradipta Ghosh, MD - University of California at San Diego

Noon                 

Panel Discussion/Q&A

12:20 p.m.         

Drug Development in 2025: Challenges and Solutions in Maximizing the Intersection Between Academia and Industry

Peter Schultz, PhD – Scripps Research San Diego

1 p.m.                 Lunch

CONTROVERSIES IN CLINICAL TRIALS: THE GI’S PERSPECTIVE

Moderator: Siddharth Singh, MD

2 p.m.                           

PROs as Endpoints

Marla Dubinsky, MD – Mount Sinai New York

2:15 p.m.                           

Intestinal Ultrasound as a Treat to Target Endpoint

Gauree Gupta Konijeti, MD, MPH – Scripps Clinic San Diego

2:30 p.m.            

Advanced Therapies in Phase 2 and Phase 3 -- Which Trials to Participate in and the Biggest Challenges with Patient Recruitment

James Marion, MD – Mount Sinai New York

2:45 p.m.            

Considerations of Mild-Moderate UC and Crohn’s Phenotypes in Drug Development

Alan Moss, MD – Boston University

3 p.m.  

Rethinking Clinical Trial Design

David Rubin, MD – University of Chicago

3:15 p.m.          

Panel Discussion/Q&A

3:30 p.m.            

Break & View Exhibits

CONTROVERSIES IN CLINICAL TRIALS: THE SURGICAL PERSPECTIVE

Moderators: Phillip Fleshner, MD and Paulo Kotze MD, PhD

4 p.m.  

Surgical Technique Decreasing Postoperative Recurrence – Close the Door or Expand on What’s Been Done?

Andre D’Hoore, MD, PhD – IBD Leuven Belgium

4:15 p.m.                           

Your Ulcerative Colitis Operation Could be Preventative – Do an Appendectomy!

Willem Bemelman, MD, PhD - Amsterdam University Medical Center

4:30 p.m.                           

MSCs and What’s Next for Perianal Fistula

Amy Lightner, MD – Scripps Clinic San Diego

4:45 p.m.                           

Top Three Surgical Trials Still to be Done

Antonino Spinelli, MD, PhD – Humanitas Milan, Italy

5 p.m.                 

Panel Discussion/Q&A

5:30 p.m.                           

Adjourn

7 a.m.                 

Breakfast & View Exhibits

7: 55 a.m.           

Welcome & Announcements

Gauree Gupta Konijeti, MD, MPH – Scripps Clinic San Diego

COFFEE & DEBATES

Moderators: David Rubin, MD and Antonino Spinelli, MD, PhD

8 a.m.  

Colectomy or Not with High Grade Dysplasia

PRO: Janindra Warusavitarne, B Med, FRACS, PhD - St. Mark’s Hospital London

CON: TBD

8:25 a.m.            

Crohn’s and Indeterminate Colitis – To Pouch or Not to Pouch

PRO: Phillip Fleshner, MD – Cedars-Sinai Medical Center

CON: Marla Dubinsky, MD - Mount Sinai New York

APPLYING CLINICAL TRIALS IN GI AND SURGERY

Moderators: Willem Bemelman, MD, PhD and Jeannie Huang, MD

8:50 a.m.                           

Evolving Demographics of the IBD Patient Population: How Do We Address It?

Alan Moss, MD – Boston University

9:20 a.m.                           

Applying Clinical Trial Results to the Pediatric Population

Jeannie Huang, MD – Rady Children’s Hospital San Diego

9:35 a.m.                           

Applying Clinical Trial Results to Pouches

Edward Barnes, MD – UNC School of Medicine

9:50 a.m.            

Rethinking Early Surgery in Crohn’s

Paulo Kotze, MD, PhD – Catholic University of Parana Curitaba, Brazil

10:05 a.m.         

Perianal Crohn’s Disease Activity Index and MRI – More than Measurements

Phil Tozer, MBBS – St. Mark’s Hospital London

10:20 a.m.         

Panel Discussion/Q&A

10:45 a.m.         

Break & View Exhibits

CHOOSING AMONG THE PLETHORA OF MEDICAL THERAPIES

Moderator: Maria Abreu, MD

11:10 a.m.         

Subcutaneous Infliximab and Vedolizumab

Mazer Ally, MD – Scripps Clinic San Diego

11:20 a.m.         

Anti-IL23 Therapies

Edward Barnes, MD – University of North Carolina

11:35 a.m.         

S1P Inhibitors

Gauree Gupta Konijeti, MD, MPH – Scripps Clinic San Diego

11:45 a.m.         

JAK Inhibitors

Brigid Boland, MD - University of California San Diego

Noon    

Crohn’s Guidelines

Siddharth Singh, MD – University of California San Diego

12:20 p.m.         

UC Guidelines

David Rubin, MD – University of Chicago

12:40 p.m.         

Panel Discussion/Q&A

1 p.m.                 

Lunch Symposium A

Non-CME Activity Hosted by AbbVie

1 p.m.  

Lunch Symposium B

Non-CME Activity Hosted by Janssen

BRINGING IT ALL TOGETHER – WHAT WE DO BEST! CLINICAL CASES WITH YOUR MULTIDISCIPLINARY TEAM

Moderators: Phillip Fleshner, MD and James Marion, MD

2 p.m.                 

Perioperative Optimization Before IBD Surgery

Gil Melmed, MD – Cedars-Sinai Medical Center

2:15 p.m.                           

Medical Management of Acute Severe UC: What to Rule Out, What Are Your Medications, And What to Watch Out For

Marla Dubinsky, MD - Mt Sinai New York

2:30 p.m.                           

Surgical Techniques, Now and in the Future

Antonino Spinelli, MD, PhD – Humanitas Milan, Italy

2:45 p.m.                           

CASE PRESENTATION: Acute-Severe UC

Panel: Willem Bemelman, MD, PhD, Marla Dubinsky, BA, PhD, Gil Melmed, MD, and Antonino Spinelli, MD, PhD

3:15 p.m.                           

Break & View Exhibits

Moderators: Gauree Gupta Konijeti, MD, MPH and Amy Lightner, MD

3:30 p.m.            

Optimizing the Medical Management of Perianal Fistula

Ailsa Hart BA, BMBCh, FRCP, PhD - St. Mark’s Hospital London

3:45 p.m.            

Does Diversion have a Role in the Management of Perianal Disease?

Andre D’Hoore MD PhD – Belgium

4 p.m.                 

The Importance of the Patient Voice in Considering Outcome Measures

Tina Aswani-Omprakash, MPH - South Asian IBD Alliance

4:15 p.m.                           

CASE PRESENTATION: Refractory Perianal Fistulizing Disease

Panel: Mazer Ally, MD, Marla Dubinsky, MD, Phil Tozer, MD, and Janindra Warusavitarne, B Med, FRACS, PhD

4:45 p.m.                           

Adjourn

5 p.m.                 

Welcome Reception

Non-CME Activity Hosted by Takeda

7 a.m.                 

Breakfast & View Exhibits

7:55 a.m.                           

Welcome & Announcements

Siddharth Singh, MD – University of California San Diego

Moderators: Paulo Kotze, MD and Alan Moss, MD

8 a.m.                 

Endoscopic Therapies for Stricturing Crohn’s Disease

Mazer Ally, MD – Scripps Clinic San Diego

8:15 a.m.                           

What the Data Shows About Using Two Advanced Therapies at the Same Time

Maria Abreu, MD – Cedars-Sinai Medical Center

8:30 a.m.                           

Postoperative Prophylaxis in Crohn’s Disease – Keeping the Surgeon Away!

Preetika Sinh, MD – University of California San Diego

Moderators: Maria Abreu, MD and Phillip Fleshner, MD

8:45 a.m.                           

CASE PRESENTATION: Terminal Ileal Crohn’s Disease

Panel: Edward Barnes MD, Brigid Boland, MD, Paulo Kotze, MD, PhD and Alan Moss, MD

DAY-TO-DAY REALITIES OF CLINICAL PRACTICE

Moderators: Gauree Gupta Konijeti, MD, MPH and Siddharth Singh, MD

9:15 a.m.                           

Use of Diet and Supplements in IBD

Lori Beeken, MS, RDN – Scripps Clinic San Diego

9:30 a.m.                           

IBD and Pregnancy

Brigid Boland, MD - University of California San Diego

9:45 a.m.                           

Update in the Management of Pediatric IBD

Jeannie Huang, MD – Rady Children’s Hospital San Diego

10 a.m.               

Dermatology & IBD

Charisse Orme, MD, PhD - University of California San Diego

10:15 a.m.         

Panel Discussion/Q&A

10:45 a.m.         

Main Conference Adjourns

*Topics, times and speakers are subject to change

10:45 a.m.               

Refreshment Break for APP Track Attendees

11:15 a.m.         

Welcome & Educational Overview

Angelina Collins, MSN, ANP-BC and Melissa Ferrari, PA-C

11:30 a.m.         

APP Digest: Medications 

Angelina Collins, MSN, ANP-BC – University of California San Diego

11:45 a.m.         

APP Digest: Special Populations

Melissa Ferrari, PA-C – Scripps Clinic San Diego

Noon                   

APP Digest: Surgery

TBD

12:15 p.m.         

Panel Discussion/Q&A

12:45 p.m.         

Advanced Practice Provider Track Adjourns