Clinical Trial to study the effectiveness of Dupilumab on AERD
- Trial ID:
- IRB-23-8183
- Andrew A. White, M.D.
Inclusion Criteria
Patients must:
- Be, at least, 18 years old.
Have a known history of nasal polyposis.
Be currently prescribed and taking dupilumab 300mg subcutaneously every 2 weeks for nasal polyposis or eosinophilic asthma.
Exclusion Criteria
Patients must not:
- Have a history of gastrointestinal reactions during NSAID triggered events.
Have unstable asthma or history of severe reactions during previous desensitization attempts.
Be unable to take montelukast.
Have a history of gastrointestinal bleeding or a bleeding disorder.
Be pregnant.
Have used an asthma biologic, other than dupilumab, in the past 3 months.
Have recently needed systemic corticosteroids to stabilize their asthma.
Have had any sinus surgery in the previous 4 weeks.
Additional Info
All study visits will occur at Scripps Clinic Carmel Valley. Study visits will include pulmonary testing and an aspirin desensitization/challenge. The aspirin desensitization will last 1 to 2 days (approximately 8 hours per day).Contact Info:
- Clinical Research Services
- CRSLeadership@scrippshealth.org
Why isn't this trial accepting new patients?
The trial may have a limited enrollment number, reached its maximum, or come to the end of its enrollment period. View trials that are recruiting
How else can Scripps help me?
We have a broad range of physician expertise and specialized medical services available. You can find a doctor online, call 1-800-SCRIPPS (1-800-727-4777) for personal help, or see related Scripps services.
How can I find trials that are accepting new participants?
For more information, see a list of trials that are recruiting, or call the clinical research office at 858-648-6402 for help.